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[ P01.01. INTRODUCTION ]
[ P01.01. INTRODUCTION ]
Matrica Materials Corporation.
Matrica Materials Corporation.
We are engineering a topically applied, surgical-caliber anti-aging gel for people who believe that graceful aging does not include face lifts and painful office procedures.
We are engineering a topically applied, surgical-caliber anti-aging gel for people who believe that graceful aging does not include face lifts and painful office procedures.
The price is $28,500 per year. It is applied at home, 7-10 consecutive nights per month. It is available by inquiry to forty-five individuals in the first year.
The price is $28,500 per year. It is applied at home, 7-10 consecutive nights per month. It is available by inquiry to forty-five individuals in the first year.
[ P01.02. PHILOSOPHY ]
[ P01.02. PHILOSOPHY ]
Our lens is maximalism. Not conventionalism.
Reconstructive. Not cosmetic.
Our lens is maximalism.
Not conventionalism.
Reconstructive. Not cosmetic.
We define maximalism as the pursuit of the superlative.
We define maximalism as the pursuit of the superlative.
And that pursuit means discarding all usual constraints and requirements.
And that pursuit means discarding all usual constraints and requirements.
Cost-driven rules we do not follow:
Cost-driven rules we do not follow:
•
Using cosmetic or food-grade derivatives instead of the original parent molecule.
Using cosmetic or food-grade derivatives instead of the original parent molecule.
•
Subtherapeutic concentrations of each molecule.
Subtherapeutic concentrations of each molecule.
•
A twenty-four month shelf life so a product can stay in a store longer until it’s purchased.
A twenty-four month shelf life so a product can stay in a store longer until it’s purchased.
•
Combining molecules and eluents into a single vessel when separation drives superior efficacy.
Combining molecules and eluents into a single vessel when separation drives superior efficacy.
[ P01.03. OUR TEAM ]
[ P01.03. OUR TEAM ]
Our team is composed of engineers who have developed surgical biomaterials for decades, plastic surgeons who have operated on full-thickness burns and battlefield injuries, and scientists who solely specialize in complex macromolecule drug delivery.
Our team is composed of engineers who have developed surgical biomaterials for decades, plastic surgeons who have operated on full-thickness burns and battlefield injuries, and scientists who solely specialize in complex macromolecule drug delivery.
Our titles or job descriptions never started with the word “cosmetic.”
Our titles or job descriptions never started with the word “cosmetic.”
We’ve committed ourselves to the preservation of the face, because the face is the first introduction to every room, every endeavor, every phase still ahead.
We’ve committed ourselves to the preservation of the face, because the face is the first introduction to every room, every endeavor, every phase still ahead.
[ P01.04. OUR APPROACH ]
[ P01.04. OUR APPROACH ]
That introduction begins at the deepest structural layer: the extracellular matrix.
That introduction begins at the deepest structural layer: the extracellular matrix.
Our engineering will help rebuild and support the extracellular matrix, the structural foundation of the skin, using molecules, materials, and delivery methods unavailable to and unconsidered even by “clinical” skincare.
Our engineering will help rebuild and support the extracellular matrix, the structural foundation of the skin, using molecules, materials, and delivery methods unavailable to and unconsidered even by “clinical” skincare.
MEDICAL DEVICE STANDARD
COSMETIC STANDARD
Manufacturing Standards
QMS & Safety
ISO 13485 medical device QMS.
ISO 22442 for animal-derived tissue.
ISO 10993 for human biocompatibility.
ISO 22716 cosmetics GMP.
No implantability or incompatibility requirements
Sterility
Terminally sterilized to SAL 10⁻⁶ .
e.g., EO per ISO 11135, gamma per ISO 11137
Sterility tests: 0 CFU growth.
ISO 11737-2
Not required to be sterile. 1,000 CFU/g limit.
Endotoxin
Pyrogen
≤ 0.5 EU/mL
for implantable devices.
No endotoxin standards. Typically 5.0 EU/mL is considered acceptable.
Traceability
Full batch traceability to tissue lot.
Controlled donor/species documentation.
Validated removal/inactivation steps.
Ingredient CoA and supplier traceability.
No tissue‑level device traceability.
Manufacturing Standards
QMS & Safety
MEDICAL DEVICE
COSMETIC STANDARD
ISO 13485
medical device QMS
ISO 22442
for animal-derived tissue
ISO 10993
for human biocompatibility
ISO 22716 cosmetics GMP.
No implantability or incompatibility requirements.
Sterility
MEDICAL DEVICE
COSMETIC STANDARD
Terminally sterilized
to SAL 10⁻⁶
e.g., EO per ISO 11135, gamma per ISO 11137
Sterility tests
0 CFU growth.
ISO 11737-2
Not required to be sterile. 1,000 CFU/g limit.
Endotoxin
Pyrogen
MEDICAL DEVICE
COSMETIC STANDARD
≤ 0.5 EU/mL
for implantable devices
No endotoxin standards. Typically 5.0 EU/mL is considered acceptable.
Traceability
MEDICAL DEVICE
COSMETIC STANDARD
Full batch traceability
to tissue lot
Controlled
donor/species documentation
Validated removal/ inactivation steps.
Ingredient CoA and supplier traceability
No tissue‑level device traceability.
[ P01.05. MECHANISMS OF AGING ]
[ P01.05. MECHANISMS OF AGING ]
The visible consequences of molecular aging are familiar:
The visible consequences of molecular aging are familiar:
•
Progressive skin laxity as load-bearing ability declines.
Progressive skin laxity as load-bearing ability declines.
•
Fine lines become more fixed as dermal support reduces.
Fine lines become more fixed as dermal support reduces.
•
Crepey texture and translucency as matrix density diminishes.
Crepey texture and translucency as matrix density diminishes.
These are the result of structural failure within the dermis.
These are the result of structural failure within the dermis.
Currently, cosmetic endeavors may support collagen synthesis, but ignore the structural conditions under which it is formed.
Currently, cosmetic endeavors may support collagen synthesis, but ignore the structural conditions under which it is formed.
A superlative technology must not only drive collagen synthesis, but also its assembly and preservation, by acting on key cellular mechanisms:
A superlative technology must not only drive collagen synthesis, but also its assembly and preservation, by acting on key cellular mechanisms:
•
Signaling fibroblasts within the extracellular matrix with structurally native cues for collagen synthesis. Strong signaling of fibroblasts requires native signaling motifs transported to the extracellular matrix in the dermal layer1.
Signaling fibroblasts within the extracellular matrix with structurally native cues for collagen synthesis. Strong signaling of fibroblasts requires native signaling motifs transported to the extracellular matrix in the dermal layer1.
•
Organizing the assembly of newly synthesised collagen. Synthesizing collagen is insufficient without ensuring the new collagen fibrils form into structurally sound fibers that provide load-bearing support.
Organizing the assembly of newly synthesised collagen. Synthesizing collagen is insufficient without ensuring the new collagen fibrils form into structurally sound fibers that provide load-bearing support.
•
Preserving the new collagen structure. Down-regulation of the enzymes that degrade collagen will preserve
what is being built.
Preserving the new collagen structure. Down-regulation of the enzymes that degrade collagen will preserve
what is being built.
[ P01.06. OUR STANDARD ]
[ P01.06. OUR STANDARD ]
This maximalist standard does not begin and end with science.
This maximalist standard does not begin and end with science.
The same rigor that governs our tissue sourcing and our surgical-caliber manufacturing governs every interaction with the people who place their trust in us.
The same rigor that governs our tissue sourcing and our surgical-caliber manufacturing governs every interaction with the people who place their trust in us.
In the first year following release, forty-five individuals across the UK, the US, Europe, and Singapore will have allocation to the Matrica technology.
In the first year following release, forty-five individuals across the UK, the US, Europe, and Singapore will have allocation to the Matrica technology.
To that end, this technology is being validated at our sole expense.
To that end, this technology is being validated at our sole expense.
Thereafter, each customer may refer two individuals per year. We expect to deliver to the forty-five within fourteen months of closing allocation.
Thereafter, each customer may refer two individuals per year. We expect to deliver to the forty-five within fourteen months of closing allocation.
To become one of the forty-five, we require a $5,000 deposit held in escrow.2
[2] When the product is ready for dispatch, the remaining balance of $22,500, plus any applicable taxes or duties, will be invoiced.
To become one of the forty-five, we require a $5,000 deposit held in escrow.2
[2] When the product is ready for dispatch, the remaining balance of $22,500, plus any applicable taxes or duties, will be invoiced.
Escrow funds are held by a third party and cannot be used for any R&D or operations purposes. If at any time you choose not to proceed, your escrow will be returned in full.
Escrow funds are held by a third party and cannot be used for any R&D or operations purposes. If at any time you choose not to proceed, your escrow will be returned in full.
Furthermore, the forty-five will have the ability to invest in the company, should they choose, only after we have validated the technology at our sole expense.
Furthermore, the forty-five will have the ability to invest in the company, should they choose, only after we have validated the technology at our sole expense.
[ P01.07. CONTACT ]
[ P01.07. CONTACT ]
The face is our first meeting point to the world. Preserving it for the next endeavor demands the superlative.
The face is our first meeting point to the world. Preserving it for the next endeavor demands the superlative.
To relay interest or direct any inquiries, kindly leave your details below:
To relay interest or direct any inquiries, kindly leave your details below:
Sincerely, Neelesh K. Mittal
Founder, Matrica Materials Corporation
Sincerely, Neelesh K. Mittal
Founder, Matrica Materials Corporation
Copyright 2026 Matrica Materials Company, Inc.
Copyright 2026 Matrica Materials Company, Inc.